Drug extraction from whole iris-ciliary body pork - Bertin Instruments

Pharmacologie

Drug extraction from whole iris-ciliary body pork

Sources: PharmOptima, Portage MI, USA

Context

PharmOptima focuses on in vivo and in vitro DM&PK and Discovery Services, providing IND & NDAenabling research protocols. High quality DM&PK and Ocular PK research are a part of the laboratory’s daily activities. PharmOptima, experienced in ophthalmology studies, currently uses Precellys to homogenize a variety of ocular tissues as cornea, conjunctiva, lens, irisciliary body, trabecular meshwork, sclera, retina, choroid, optic nerve. In this study, Minilys has been compared to current method (Precellys) to homogenize whole iris-ciliary body from pork.

Results

The analyte levels are equivalent. No difference involving the both homogenizer is detectable (See Figure 1).

 

Figure 1: LC-MS/MS analysis from Precellys Dual and Minilys sample.

Figure 1: LC-MS/MS analysis from Precellys Dual and Minilys sample.

 

img-03712-810-DU056-2

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